| Row |
Level |
Rule Name |
Subject |
Property |
Value |
| 0 |
ERROR |
duplicate_definition |
PW:0001651 |
IAO:0000115 |
The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. |
| 1 |
ERROR |
duplicate_definition |
PW:0002434 |
IAO:0000115 |
The pharmacokinetics and pharmacodynamics pathway of drugs that reduce or prevent the formation of blood clots. They are further classified depending on the blood clotting processes they affect. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. |
| 2 |
ERROR |
duplicate_definition |
PW:0000216 |
IAO:0000115 |
Polyamine metabolism plays important roles in a number of cellular processes. Spermidine and spermine are formed in two consecutive reactions carried out by distinct enzymes that employ the decarboxylated form of AdoMet as an aminopropyl donor. |
| 3 |
ERROR |
duplicate_definition |
PW:0000396 |
IAO:0000115 |
Polyamine metabolism plays important roles in a number of cellular processes. Spermidine and spermine are formed in two consecutive reactions carried out by distinct enzymes that employ the decarboxylated form of AdoMet as an aminopropyl donor. |
| 4 |
ERROR |
duplicate_definition |
PW:0000963 |
IAO:0000115 |
Phosphatidylinositol kinases represent a family of lipid kinases that phosphorylate the 3' position of the inositol ring in target substrates. They are grouped into three classes: class I further subdivided into subclass A and B, class II and class III. By far the best known and characterized is class I, particularly IA that signals downstream of receptor tyrosine kinases and engages the Akt family of kinases. |
| 5 |
ERROR |
duplicate_definition |
PW:0000965 |
IAO:0000115 |
Phosphatidylinositol kinases represent a family of lipid kinases that phosphorylate the 3' position of the inositol ring in target substrates. They are grouped into three classes: class I further subdivided into subclass A and B, class II and class III. By far the best known and characterized is class I, particularly IA that signals downstream of receptor tyrosine kinases and engages the Akt family of kinases. |
| 6 |
ERROR |
duplicate_definition |
PW:0000966 |
IAO:0000115 |
Phosphatidylinositol kinases represent a family of lipid kinases that phosphorylate the 3' position of the inositol ring in target substrates. They are grouped into three classes: class I further subdivided into subclass A and B, class II and class III. By far the best known and characterized is class I, particularly IA that signals downstream of receptor tyrosine kinases and engages the Akt family of kinases. |
| 7 |
ERROR |
duplicate_definition |
PW:0001580 |
IAO:0000115 |
Long non-coding RNA transcripts are subject to processing in a manner analogous to mRNA thereby they are capped and polyadenylated, and also frequently spliced. |
| 8 |
ERROR |
duplicate_definition |
PW:0001581 |
IAO:0000115 |
Long non-coding RNA transcripts are subject to processing in a manner analogous to mRNA thereby they are capped and polyadenylated, and also frequently spliced. |
| 9 |
ERROR |
duplicate_definition |
PW:0001582 |
IAO:0000115 |
Long non-coding RNA transcripts are subject to processing in a manner analogous to mRNA thereby they are capped and polyadenylated, and also frequently spliced. |
| 10 |
ERROR |
duplicate_definition |
PW:0000228 |
IAO:0000115 |
Based on sequence similarity, the Galpha genes have been grouped into four classes. Exchange of GDP to GTP promoted through binding to receptors dissociates the heterotrimeric Galpha/beta/gamma complex. GTP-bound Galpha can then interact with downstream effectors. Lipid modification of Galpha regulates membrane localization and interactions with specific effectors. |
| 11 |
ERROR |
duplicate_definition |
PW:0000229 |
IAO:0000115 |
Based on sequence similarity, the Galpha genes have been grouped into four classes. Exchange of GDP to GTP promoted through binding to receptors dissociates the heterotrimeric Galpha/beta/gamma complex. GTP-bound Galpha can then interact with downstream effectors. Lipid modification of Galpha regulates membrane localization and interactions with specific effectors. |
| 12 |
ERROR |
duplicate_definition |
PW:0000227 |
IAO:0000115 |
Based on sequence similarity, the Galpha genes have been grouped into four classes. Exchange of GDP to GTP promoted through binding to receptors dissociates the heterotrimeric Galpa/beta/gamma complex. GTP-bound Galpha can then interact with downstream effectors. Lipid modification of Galpha regulates membrane localization and interactions with specific effectors. |
| 13 |
ERROR |
duplicate_definition |
PW:0000230 |
IAO:0000115 |
Based on sequence similarity, the Galpha genes have been grouped into four classes. Exchange of GDP to GTP promoted through binding to receptors dissociates the heterotrimeric Galpa/beta/gamma complex. GTP-bound Galpha can then interact with downstream effectors. Lipid modification of Galpha regulates membrane localization and interactions with specific effectors. |
| 14 |
ERROR |
duplicate_label |
PW:0001072 |
rdfs:label |
synaptic vesicle cycle pathway |
| 15 |
ERROR |
duplicate_label |
PW:0002423 |
rdfs:label |
synaptic vesicle cycle pathway |
| 16 |
ERROR |
duplicate_label |
PW:0002020 |
rdfs:label |
nervous system lysosomal storage disease pathway |
| 17 |
ERROR |
duplicate_label |
PW:0002300 |
rdfs:label |
nervous system lysosomal storage disease pathway |
| 18 |
ERROR |
duplicate_label |
PW:0000166 |
rdfs:label |
monoterpenoid biosynthetic pathway |
| 19 |
ERROR |
duplicate_label |
PW:0000252 |
rdfs:label |
monoterpenoid biosynthetic pathway |
| 20 |
ERROR |
duplicate_label |
PW:0002289 |
rdfs:label |
malonic aciduria pathway |
| 21 |
ERROR |
duplicate_label |
PW:0002550 |
rdfs:label |
malonic aciduria pathway |
| 22 |
ERROR |
duplicate_label |
PW:0001081 |
rdfs:label |
lysine metabolic pathway |
| 23 |
ERROR |
duplicate_label |
PW:0002185 |
rdfs:label |
lysine metabolic pathway |
| 24 |
ERROR |
duplicate_label |
PW:0001413 |
rdfs:label |
liver disease pathway |
| 25 |
ERROR |
duplicate_label |
PW:0001698 |
rdfs:label |
liver disease pathway |
| 26 |
ERROR |
duplicate_label |
PW:0002304 |
rdfs:label |
indometacin pharmacokinetics pathway |
| 27 |
ERROR |
duplicate_label |
PW:0002314 |
rdfs:label |
indometacin pharmacokinetics pathway |
| 28 |
ERROR |
duplicate_label |
PW:0002305 |
rdfs:label |
indometacin pharmacodynamics pathway |
| 29 |
ERROR |
duplicate_label |
PW:0002315 |
rdfs:label |
indometacin pharmacodynamics pathway |
| 30 |
ERROR |
duplicate_label |
PW:0002303 |
rdfs:label |
indometacin drug pathway |
| 31 |
ERROR |
duplicate_label |
PW:0002313 |
rdfs:label |
indometacin drug pathway |
| 32 |
ERROR |
duplicate_label |
PW:0001868 |
rdfs:label |
hypermethioninemia pathway |
| 33 |
ERROR |
duplicate_label |
PW:0002471 |
rdfs:label |
hypermethioninemia pathway |
| 34 |
ERROR |
duplicate_label |
PW:0001138 |
rdfs:label |
ether lipid metabolic pathway |
| 35 |
ERROR |
duplicate_label |
PW:0001157 |
rdfs:label |
ether lipid metabolic pathway |
| 36 |
ERROR |
duplicate_label |
PW:0000565 |
rdfs:label |
eicosanoid signaling pathway |
| 37 |
ERROR |
duplicate_label |
PW:0001294 |
rdfs:label |
eicosanoid signaling pathway |
| 38 |
ERROR |
duplicate_label |
PW:0001736 |
rdfs:label |
adrenergic beta receptor agonist drug pathway |
| 39 |
ERROR |
duplicate_label |
PW:0002498 |
rdfs:label |
adrenergic beta receptor agonist drug pathway |
| 40 |
ERROR |
missing_ontology_description |
http://purl.obolibrary.org/obo/pw.owl |
dc:description |
|
| 41 |
ERROR |
missing_ontology_license |
http://purl.obolibrary.org/obo/pw.owl |
dc:license |
|
| 42 |
ERROR |
missing_ontology_title |
http://purl.obolibrary.org/obo/pw.owl |
dc:title |
|
| 43 |
WARN |
annotation_whitespace |
PW:0000311 |
IAO:0000115 |
Fibrinoid necrosis involves the deposition of fibrin and other plasma proteins in the walls of afferent renal arterioles in maligt hypertension, often accompanied by an inflammatory infiltrate within the walls and thrombosis of the vessel lumen. |
| 44 |
WARN |
duplicate_label_synonym |
PW:0001478 |
oboInOwl:hasExactSynonym |
congenital adrenal hyperplasia pathway |
| 45 |
WARN |
duplicate_label_synonym |
PW:0001808 |
oboInOwl:hasExactSynonym |
nonketotic hyperglycinemia pathway |
| 46 |
WARN |
duplicate_label_synonym |
PW:0002459 |
oboInOwl:hasExactSynonym |
dermatological drug pathway |
| 47 |
WARN |
missing_definition |
PW:0000066 |
IAO:0000115 |
|
| 48 |
WARN |
missing_definition |
PW:0000098 |
IAO:0000115 |
|
| 49 |
WARN |
missing_definition |
PW:0000148 |
IAO:0000115 |
|
| 50 |
WARN |
missing_definition |
PW:0000149 |
IAO:0000115 |
|
| 51 |
WARN |
missing_definition |
PW:0000150 |
IAO:0000115 |
|
| 52 |
WARN |
missing_definition |
PW:0000207 |
IAO:0000115 |
|
| 53 |
WARN |
missing_definition |
PW:0000257 |
IAO:0000115 |
|
| 54 |
WARN |
missing_definition |
PW:0000272 |
IAO:0000115 |
|
| 55 |
WARN |
missing_definition |
PW:0000326 |
IAO:0000115 |
|
| 56 |
WARN |
missing_definition |
PW:0000334 |
IAO:0000115 |
|
| 57 |
WARN |
missing_definition |
PW:0000338 |
IAO:0000115 |
|
| 58 |
WARN |
missing_definition |
PW:0000339 |
IAO:0000115 |
|
| 59 |
WARN |
missing_definition |
PW:0000344 |
IAO:0000115 |
|
| 60 |
WARN |
missing_definition |
PW:0000345 |
IAO:0000115 |
|
| 61 |
WARN |
missing_definition |
PW:0000347 |
IAO:0000115 |
|
| 62 |
WARN |
missing_definition |
PW:0000348 |
IAO:0000115 |
|
| 63 |
WARN |
missing_definition |
PW:0000361 |
IAO:0000115 |
|
| 64 |
WARN |
missing_definition |
PW:0000364 |
IAO:0000115 |
|
| 65 |
WARN |
missing_definition |
PW:0000381 |
IAO:0000115 |
|
| 66 |
WARN |
missing_definition |
PW:0000382 |
IAO:0000115 |
|
| 67 |
WARN |
missing_definition |
PW:0000383 |
IAO:0000115 |
|
| 68 |
WARN |
missing_definition |
PW:0000389 |
IAO:0000115 |
|
| 69 |
WARN |
missing_definition |
PW:0000390 |
IAO:0000115 |
|
| 70 |
WARN |
missing_definition |
PW:0000391 |
IAO:0000115 |
|
| 71 |
WARN |
missing_definition |
PW:0000393 |
IAO:0000115 |
|
| 72 |
WARN |
missing_definition |
PW:0000395 |
IAO:0000115 |
|
| 73 |
WARN |
missing_definition |
PW:0000406 |
IAO:0000115 |
|
| 74 |
WARN |
missing_definition |
PW:0000418 |
IAO:0000115 |
|
| 75 |
WARN |
missing_definition |
PW:0000420 |
IAO:0000115 |
|
| 76 |
WARN |
missing_definition |
PW:0000422 |
IAO:0000115 |
|
| 77 |
WARN |
missing_definition |
PW:0000428 |
IAO:0000115 |
|
| 78 |
WARN |
missing_definition |
PW:0000429 |
IAO:0000115 |
|
| 79 |
WARN |
missing_definition |
PW:0000437 |
IAO:0000115 |
|
| 80 |
WARN |
missing_definition |
PW:0000445 |
IAO:0000115 |
|
| 81 |
WARN |
missing_definition |
PW:0000446 |
IAO:0000115 |
|
| 82 |
WARN |
missing_definition |
PW:0000447 |
IAO:0000115 |
|
| 83 |
WARN |
missing_definition |
PW:0000466 |
IAO:0000115 |
|
| 84 |
WARN |
missing_definition |
PW:0000467 |
IAO:0000115 |
|
| 85 |
WARN |
missing_definition |
PW:0000476 |
IAO:0000115 |
|
| 86 |
WARN |
missing_definition |
PW:0000496 |
IAO:0000115 |
|
| 87 |
WARN |
missing_definition |
PW:0000497 |
IAO:0000115 |
|
| 88 |
WARN |
missing_definition |
PW:0000500 |
IAO:0000115 |
|
| 89 |
WARN |
missing_definition |
PW:0000510 |
IAO:0000115 |
|
| 90 |
WARN |
missing_definition |
PW:0000511 |
IAO:0000115 |
|
| 91 |
WARN |
missing_definition |
PW:0000525 |
IAO:0000115 |
|
| 92 |
WARN |
missing_definition |
PW:0000541 |
IAO:0000115 |
|
| 93 |
WARN |
missing_definition |
PW:0000545 |
IAO:0000115 |
|
| 94 |
WARN |
missing_definition |
PW:0000558 |
IAO:0000115 |
|
| 95 |
WARN |
missing_definition |
PW:0000601 |
IAO:0000115 |
|
| 96 |
WARN |
missing_definition |
PW:0000604 |
IAO:0000115 |
|
| 97 |
WARN |
missing_definition |
PW:0000621 |
IAO:0000115 |
|
| 98 |
WARN |
missing_definition |
PW:0000628 |
IAO:0000115 |
|
| 99 |
WARN |
missing_definition |
PW:0000630 |
IAO:0000115 |
|
| 100 |
WARN |
missing_definition |
PW:0000632 |
IAO:0000115 |
|
| 101 |
WARN |
missing_definition |
PW:0000635 |
IAO:0000115 |
|
| 102 |
WARN |
missing_definition |
PW:0000671 |
IAO:0000115 |
|
| 103 |
WARN |
missing_definition |
PW:0000672 |
IAO:0000115 |
|
| 104 |
WARN |
missing_definition |
PW:0000673 |
IAO:0000115 |
|
| 105 |
WARN |
missing_definition |
PW:0000680 |
IAO:0000115 |
|
| 106 |
WARN |
missing_definition |
PW:0000702 |
IAO:0000115 |
|
| 107 |
WARN |
missing_definition |
PW:0000785 |
IAO:0000115 |
|
| 108 |
WARN |
missing_definition |
PW:0000786 |
IAO:0000115 |
|
| 109 |
WARN |
missing_definition |
PW:0000787 |
IAO:0000115 |
|
| 110 |
WARN |
missing_definition |
PW:0000810 |
IAO:0000115 |
|
| 111 |
WARN |
missing_definition |
PW:0000819 |
IAO:0000115 |
|
| 112 |
WARN |
missing_definition |
PW:0000820 |
IAO:0000115 |
|
| 113 |
WARN |
missing_definition |
PW:0000849 |
IAO:0000115 |
|
| 114 |
WARN |
missing_definition |
PW:0000850 |
IAO:0000115 |
|
| 115 |
WARN |
missing_definition |
PW:0000880 |
IAO:0000115 |
|
| 116 |
WARN |
missing_definition |
PW:0000881 |
IAO:0000115 |
|
| 117 |
WARN |
missing_definition |
PW:0000886 |
IAO:0000115 |
|
| 118 |
WARN |
missing_definition |
PW:0000887 |
IAO:0000115 |
|
| 119 |
WARN |
missing_definition |
PW:0000889 |
IAO:0000115 |
|
| 120 |
WARN |
missing_definition |
PW:0000890 |
IAO:0000115 |
|
| 121 |
WARN |
missing_definition |
PW:0000891 |
IAO:0000115 |
|
| 122 |
WARN |
missing_definition |
PW:0000892 |
IAO:0000115 |
|
| 123 |
WARN |
missing_definition |
PW:0000893 |
IAO:0000115 |
|
| 124 |
WARN |
missing_definition |
PW:0000902 |
IAO:0000115 |
|
| 125 |
WARN |
missing_definition |
PW:0000904 |
IAO:0000115 |
|
| 126 |
WARN |
missing_definition |
PW:0000959 |
IAO:0000115 |
|
| 127 |
WARN |
missing_definition |
PW:0000964 |
IAO:0000115 |
|
| 128 |
WARN |
missing_definition |
PW:0000977 |
IAO:0000115 |
|
| 129 |
WARN |
missing_definition |
PW:0000984 |
IAO:0000115 |
|
| 130 |
WARN |
missing_definition |
PW:0000985 |
IAO:0000115 |
|
| 131 |
WARN |
missing_definition |
PW:0000986 |
IAO:0000115 |
|
| 132 |
WARN |
missing_definition |
PW:0000994 |
IAO:0000115 |
|
| 133 |
WARN |
missing_definition |
PW:0000995 |
IAO:0000115 |
|
| 134 |
WARN |
missing_definition |
PW:0000997 |
IAO:0000115 |
|
| 135 |
WARN |
missing_definition |
PW:0001001 |
IAO:0000115 |
|
| 136 |
WARN |
missing_definition |
PW:0001029 |
IAO:0000115 |
|
| 137 |
WARN |
missing_definition |
PW:0001056 |
IAO:0000115 |
|
| 138 |
WARN |
missing_definition |
PW:0001057 |
IAO:0000115 |
|
| 139 |
WARN |
missing_definition |
PW:0001068 |
IAO:0000115 |
|
| 140 |
WARN |
missing_definition |
PW:0001078 |
IAO:0000115 |
|
| 141 |
WARN |
missing_definition |
PW:0001111 |
IAO:0000115 |
|
| 142 |
WARN |
missing_definition |
PW:0001112 |
IAO:0000115 |
|
| 143 |
WARN |
missing_definition |
PW:0001116 |
IAO:0000115 |
|
| 144 |
WARN |
missing_definition |
PW:0001118 |
IAO:0000115 |
|
| 145 |
WARN |
missing_definition |
PW:0001147 |
IAO:0000115 |
|
| 146 |
WARN |
missing_definition |
PW:0001165 |
IAO:0000115 |
|
| 147 |
WARN |
missing_definition |
PW:0001166 |
IAO:0000115 |
|
| 148 |
WARN |
missing_definition |
PW:0001169 |
IAO:0000115 |
|
| 149 |
WARN |
missing_definition |
PW:0001181 |
IAO:0000115 |
|
| 150 |
WARN |
missing_definition |
PW:0001184 |
IAO:0000115 |
|
| 151 |
WARN |
missing_definition |
PW:0001187 |
IAO:0000115 |
|
| 152 |
WARN |
missing_definition |
PW:0001188 |
IAO:0000115 |
|
| 153 |
WARN |
missing_definition |
PW:0001190 |
IAO:0000115 |
|
| 154 |
WARN |
missing_definition |
PW:0001196 |
IAO:0000115 |
|
| 155 |
WARN |
missing_definition |
PW:0001197 |
IAO:0000115 |
|
| 156 |
WARN |
missing_definition |
PW:0001198 |
IAO:0000115 |
|
| 157 |
WARN |
missing_definition |
PW:0001199 |
IAO:0000115 |
|
| 158 |
WARN |
missing_definition |
PW:0001208 |
IAO:0000115 |
|
| 159 |
WARN |
missing_definition |
PW:0001209 |
IAO:0000115 |
|
| 160 |
WARN |
missing_definition |
PW:0001222 |
IAO:0000115 |
|
| 161 |
WARN |
missing_definition |
PW:0001223 |
IAO:0000115 |
|
| 162 |
WARN |
missing_definition |
PW:0001232 |
IAO:0000115 |
|
| 163 |
WARN |
missing_definition |
PW:0001238 |
IAO:0000115 |
|
| 164 |
WARN |
missing_definition |
PW:0001251 |
IAO:0000115 |
|
| 165 |
WARN |
missing_definition |
PW:0001255 |
IAO:0000115 |
|
| 166 |
WARN |
missing_definition |
PW:0001256 |
IAO:0000115 |
|
| 167 |
WARN |
missing_definition |
PW:0001258 |
IAO:0000115 |
|
| 168 |
WARN |
missing_definition |
PW:0001259 |
IAO:0000115 |
|
| 169 |
WARN |
missing_definition |
PW:0001306 |
IAO:0000115 |
|
| 170 |
WARN |
missing_definition |
PW:0001308 |
IAO:0000115 |
|
| 171 |
WARN |
missing_definition |
PW:0001313 |
IAO:0000115 |
|
| 172 |
WARN |
missing_definition |
PW:0001314 |
IAO:0000115 |
|
| 173 |
WARN |
missing_definition |
PW:0001325 |
IAO:0000115 |
|
| 174 |
WARN |
missing_definition |
PW:0001326 |
IAO:0000115 |
|
| 175 |
WARN |
missing_definition |
PW:0001347 |
IAO:0000115 |
|
| 176 |
WARN |
missing_definition |
PW:0001351 |
IAO:0000115 |
|
| 177 |
WARN |
missing_definition |
PW:0001352 |
IAO:0000115 |
|
| 178 |
WARN |
missing_definition |
PW:0001353 |
IAO:0000115 |
|
| 179 |
WARN |
missing_definition |
PW:0001368 |
IAO:0000115 |
|
| 180 |
WARN |
missing_definition |
PW:0001389 |
IAO:0000115 |
|
| 181 |
WARN |
missing_definition |
PW:0001398 |
IAO:0000115 |
|
| 182 |
WARN |
missing_definition |
PW:0001459 |
IAO:0000115 |
|
| 183 |
WARN |
missing_definition |
PW:0001460 |
IAO:0000115 |
|
| 184 |
WARN |
missing_definition |
PW:0001461 |
IAO:0000115 |
|
| 185 |
WARN |
missing_definition |
PW:0001492 |
IAO:0000115 |
|
| 186 |
WARN |
missing_definition |
PW:0001493 |
IAO:0000115 |
|
| 187 |
WARN |
missing_definition |
PW:0001494 |
IAO:0000115 |
|
| 188 |
WARN |
missing_definition |
PW:0001496 |
IAO:0000115 |
|
| 189 |
WARN |
missing_definition |
PW:0001500 |
IAO:0000115 |
|
| 190 |
WARN |
missing_definition |
PW:0001501 |
IAO:0000115 |
|
| 191 |
WARN |
missing_definition |
PW:0001505 |
IAO:0000115 |
|
| 192 |
WARN |
missing_definition |
PW:0001519 |
IAO:0000115 |
|
| 193 |
WARN |
missing_definition |
PW:0001536 |
IAO:0000115 |
|
| 194 |
WARN |
missing_definition |
PW:0001537 |
IAO:0000115 |
|
| 195 |
WARN |
missing_definition |
PW:0001538 |
IAO:0000115 |
|
| 196 |
WARN |
missing_definition |
PW:0001540 |
IAO:0000115 |
|
| 197 |
WARN |
missing_definition |
PW:0001541 |
IAO:0000115 |
|
| 198 |
WARN |
missing_definition |
PW:0001543 |
IAO:0000115 |
|
| 199 |
WARN |
missing_definition |
PW:0001544 |
IAO:0000115 |
|