ROBOT Report - txpo

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Types of errors

LevelNumber of errors
WARN2110
INFO112
ERROR7

Error breakdown

RuleNumber of errors
missing_definition1781
invalid_xref178
duplicate_exact_synonym142
lowercase_definition112
duplicate_label_synonym7
duplicate_definition4
duplicate_label2
equivalent_class_axiom_no_genus2
missing_ontology_license1

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Row Level Rule Name Subject Property Value
0 ERROR duplicate_definition TXPO:0003986 IAO:0000115 Sphingomyelin homeostasis imbalance is a subtype of lipid homeostasis imbalance: A process that becomes lacking a phospholipid homeostastasis balance. This entity is a specific course-dependent process. This process can constitute the course of Niemann Pick Disease Type A.
1 ERROR duplicate_definition TXPO:0005143 IAO:0000115 Sphingomyelin homeostasis imbalance is a subtype of lipid homeostasis imbalance: A process that becomes lacking a phospholipid homeostastasis balance. This entity is a specific course-dependent process. This process can constitute the course of Niemann Pick Disease Type A.
2 ERROR duplicate_definition TXPO:0005070 IAO:0000115 Liver cancer dependent molecule is a subtype of toxic course dependent chemical entity. This gene can participate in the course of Liver cancer as a gene product. Gene profile:Mouse
3 ERROR duplicate_definition TXPO:0005072 IAO:0000115 Liver cancer dependent molecule is a subtype of toxic course dependent chemical entity. This gene can participate in the course of Liver cancer as a gene product. Gene profile:Mouse
4 ERROR duplicate_label TXPO:0001712 rdfs:label PERK-eIF2a signal transduction system
5 ERROR duplicate_label TXPO:0001725 rdfs:label PERK-eIF2a signal transduction system
6 ERROR missing_ontology_license http://purl.obolibrary.org/obo/txpo.owl dc:license
7 WARN duplicate_exact_synonym TXPO:0004869 oboInOwl:hasExactSynonym
8 WARN duplicate_exact_synonym TXPO:0005137 oboInOwl:hasExactSynonym
9 WARN duplicate_exact_synonym TXPO:0005047 oboInOwl:hasExactSynonym
10 WARN duplicate_exact_synonym TXPO:0005096 oboInOwl:hasExactSynonym
11 WARN duplicate_exact_synonym TXPO:0004857 oboInOwl:hasExactSynonym
12 WARN duplicate_exact_synonym TXPO:0004858 oboInOwl:hasExactSynonym
13 WARN duplicate_exact_synonym TXPO:0004852 oboInOwl:hasExactSynonym
14 WARN duplicate_exact_synonym TXPO:0005136 oboInOwl:hasExactSynonym
15 WARN duplicate_exact_synonym TXPO:0004093 oboInOwl:hasExactSynonym
16 WARN duplicate_exact_synonym TXPO:0004849 oboInOwl:hasExactSynonym
17 WARN duplicate_exact_synonym TXPO:0004842 oboInOwl:hasExactSynonym
18 WARN duplicate_exact_synonym TXPO:0005069 oboInOwl:hasExactSynonym
19 WARN duplicate_exact_synonym TXPO:0004449 oboInOwl:hasExactSynonym
20 WARN duplicate_exact_synonym TXPO:0004819 oboInOwl:hasExactSynonym
21 WARN duplicate_exact_synonym TXPO:0003579 oboInOwl:hasExactSynonym
22 WARN duplicate_exact_synonym TXPO:0003580 oboInOwl:hasExactSynonym
23 WARN duplicate_exact_synonym TXPO:0004812 oboInOwl:hasExactSynonym
24 WARN duplicate_exact_synonym TXPO:0005132 oboInOwl:hasExactSynonym
25 WARN duplicate_exact_synonym TXPO:0004799 oboInOwl:hasExactSynonym
26 WARN duplicate_exact_synonym TXPO:0004801 oboInOwl:hasExactSynonym
27 WARN duplicate_exact_synonym TXPO:0005131 oboInOwl:hasExactSynonym
28 WARN duplicate_exact_synonym TXPO:0001328 oboInOwl:hasExactSynonym
29 WARN duplicate_exact_synonym TXPO:0004061 oboInOwl:hasExactSynonym
30 WARN duplicate_exact_synonym TXPO:0004193 oboInOwl:hasExactSynonym
31 WARN duplicate_exact_synonym TXPO:0004678 oboInOwl:hasExactSynonym
32 WARN duplicate_exact_synonym TXPO:0004876 oboInOwl:hasExactSynonym
33 WARN duplicate_exact_synonym TXPO:0004951 oboInOwl:hasExactSynonym
34 WARN duplicate_exact_synonym TXPO:0003052 oboInOwl:hasExactSynonym
35 WARN duplicate_exact_synonym TXPO:0003053 oboInOwl:hasExactSynonym
36 WARN duplicate_exact_synonym TXPO:0001183 oboInOwl:hasExactSynonym
37 WARN duplicate_exact_synonym TXPO:0003799 oboInOwl:hasExactSynonym
38 WARN duplicate_exact_synonym TXPO:0004733 oboInOwl:hasExactSynonym
39 WARN duplicate_exact_synonym TXPO:0004736 oboInOwl:hasExactSynonym
40 WARN duplicate_exact_synonym TXPO:0003862 oboInOwl:hasExactSynonym
41 WARN duplicate_exact_synonym TXPO:0004450 oboInOwl:hasExactSynonym
42 WARN duplicate_exact_synonym TXPO:0005071 oboInOwl:hasExactSynonym
43 WARN duplicate_exact_synonym TXPO:0003285 oboInOwl:hasExactSynonym
44 WARN duplicate_exact_synonym TXPO:0003287 oboInOwl:hasExactSynonym
45 WARN duplicate_exact_synonym TXPO:0004200 oboInOwl:hasExactSynonym
46 WARN duplicate_exact_synonym TXPO:0004763 oboInOwl:hasExactSynonym
47 WARN duplicate_exact_synonym TXPO:0004885 oboInOwl:hasExactSynonym
48 WARN duplicate_exact_synonym TXPO:0005119 oboInOwl:hasExactSynonym
49 WARN duplicate_exact_synonym TXPO:0004840 oboInOwl:hasExactSynonym
50 WARN duplicate_exact_synonym TXPO:0004841 oboInOwl:hasExactSynonym
51 WARN duplicate_exact_synonym TXPO:0004538 oboInOwl:hasExactSynonym
52 WARN duplicate_exact_synonym TXPO:0004572 oboInOwl:hasExactSynonym
53 WARN duplicate_exact_synonym TXPO:0001922 oboInOwl:hasExactSynonym
54 WARN duplicate_exact_synonym TXPO:0004331 oboInOwl:hasExactSynonym
55 WARN duplicate_exact_synonym TXPO:0004639 oboInOwl:hasExactSynonym
56 WARN duplicate_exact_synonym TXPO:0005094 oboInOwl:hasExactSynonym
57 WARN duplicate_exact_synonym TXPO:0001123 oboInOwl:hasExactSynonym
58 WARN duplicate_exact_synonym TXPO:0001124 oboInOwl:hasExactSynonym
59 WARN duplicate_exact_synonym TXPO:0002385 oboInOwl:hasExactSynonym
60 WARN duplicate_exact_synonym TXPO:0004578 oboInOwl:hasExactSynonym
61 WARN duplicate_exact_synonym TXPO:0002619 oboInOwl:hasExactSynonym
62 WARN duplicate_exact_synonym TXPO:0002677 oboInOwl:hasExactSynonym
63 WARN duplicate_exact_synonym TXPO:0003476 oboInOwl:hasExactSynonym
64 WARN duplicate_exact_synonym TXPO:0004210 oboInOwl:hasExactSynonym
65 WARN duplicate_exact_synonym TXPO:0004894 oboInOwl:hasExactSynonym
66 WARN duplicate_exact_synonym TXPO:0004895 oboInOwl:hasExactSynonym
67 WARN duplicate_exact_synonym TXPO:0000877 oboInOwl:hasExactSynonym
68 WARN duplicate_exact_synonym TXPO:0001172 oboInOwl:hasExactSynonym
69 WARN duplicate_exact_synonym TXPO:0003281 oboInOwl:hasExactSynonym
70 WARN duplicate_exact_synonym TXPO:0004665 oboInOwl:hasExactSynonym
71 WARN duplicate_exact_synonym TXPO:0004645 oboInOwl:hasExactSynonym
72 WARN duplicate_exact_synonym TXPO:0004647 oboInOwl:hasExactSynonym
73 WARN duplicate_exact_synonym TXPO:0005095 oboInOwl:hasExactSynonym
74 WARN duplicate_exact_synonym TXPO:0004592 oboInOwl:hasExactSynonym
75 WARN duplicate_exact_synonym TXPO:0005018 oboInOwl:hasExactSynonym
76 WARN duplicate_exact_synonym TXPO:0005039 oboInOwl:hasExactSynonym
77 WARN duplicate_exact_synonym TXPO:0005043 oboInOwl:hasExactSynonym
78 WARN duplicate_exact_synonym TXPO:0003290 oboInOwl:hasExactSynonym
79 WARN duplicate_exact_synonym TXPO:0005034 oboInOwl:hasExactSynonym
80 WARN duplicate_exact_synonym TXPO:0005042 oboInOwl:hasExactSynonym
81 WARN duplicate_exact_synonym TXPO:0005044 oboInOwl:hasExactSynonym
82 WARN duplicate_exact_synonym TXPO:0001002 oboInOwl:hasExactSynonym
83 WARN duplicate_exact_synonym TXPO:0004194 oboInOwl:hasExactSynonym
84 WARN duplicate_exact_synonym TXPO:0004616 oboInOwl:hasExactSynonym
85 WARN duplicate_exact_synonym TXPO:0004602 oboInOwl:hasExactSynonym
86 WARN duplicate_exact_synonym TXPO:0005098 oboInOwl:hasExactSynonym
87 WARN duplicate_exact_synonym TXPO:0004623 oboInOwl:hasExactSynonym
88 WARN duplicate_exact_synonym TXPO:0004626 oboInOwl:hasExactSynonym
89 WARN duplicate_exact_synonym TXPO:0004608 oboInOwl:hasExactSynonym
90 WARN duplicate_exact_synonym TXPO:0005089 oboInOwl:hasExactSynonym
91 WARN duplicate_exact_synonym TXPO:0001014 oboInOwl:hasExactSynonym
92 WARN duplicate_exact_synonym TXPO:0001017 oboInOwl:hasExactSynonym
93 WARN duplicate_exact_synonym TXPO:0001022 oboInOwl:hasExactSynonym
94 WARN duplicate_exact_synonym TXPO:0001024 oboInOwl:hasExactSynonym
95 WARN duplicate_exact_synonym TXPO:0002365 oboInOwl:hasExactSynonym
96 WARN duplicate_exact_synonym TXPO:1000163 oboInOwl:hasExactSynonym
97 WARN duplicate_exact_synonym TXPO:0000856 oboInOwl:hasExactSynonym
98 WARN duplicate_exact_synonym TXPO:0000857 oboInOwl:hasExactSynonym
99 WARN duplicate_exact_synonym TXPO:0000563 oboInOwl:hasExactSynonym
100 WARN duplicate_exact_synonym TXPO:0003674 oboInOwl:hasExactSynonym
101 WARN duplicate_exact_synonym TXPO:0003706 oboInOwl:hasExactSynonym
102 WARN duplicate_exact_synonym TXPO:0003707 oboInOwl:hasExactSynonym
103 WARN duplicate_exact_synonym TXPO:0004389 oboInOwl:hasExactSynonym
104 WARN duplicate_exact_synonym TXPO:0004972 oboInOwl:hasExactSynonym
105 WARN duplicate_exact_synonym TXPO:0004547 oboInOwl:hasExactSynonym
106 WARN duplicate_exact_synonym TXPO:0005130 oboInOwl:hasExactSynonym
107 WARN duplicate_exact_synonym TXPO:0000087 oboInOwl:hasExactSynonym
108 WARN duplicate_exact_synonym TXPO:0000783 oboInOwl:hasExactSynonym
109 WARN duplicate_exact_synonym TXPO:0000801 oboInOwl:hasExactSynonym
110 WARN duplicate_exact_synonym TXPO:0003471 oboInOwl:hasExactSynonym
111 WARN duplicate_exact_synonym TXPO:0000878 oboInOwl:hasExactSynonym
112 WARN duplicate_exact_synonym TXPO:0002880 oboInOwl:hasExactSynonym
113 WARN duplicate_exact_synonym TXPO:0004872 oboInOwl:hasExactSynonym
114 WARN duplicate_exact_synonym TXPO:0005073 oboInOwl:hasExactSynonym
115 WARN duplicate_exact_synonym TXPO:0004521 oboInOwl:hasExactSynonym
116 WARN duplicate_exact_synonym TXPO:0004523 oboInOwl:hasExactSynonym
117 WARN duplicate_exact_synonym TXPO:0004851 oboInOwl:hasExactSynonym
118 WARN duplicate_exact_synonym TXPO:0004843 oboInOwl:hasExactSynonym
119 WARN duplicate_exact_synonym TXPO:0005079 oboInOwl:hasExactSynonym
120 WARN duplicate_exact_synonym TXPO:0004063 oboInOwl:hasExactSynonym
121 WARN duplicate_exact_synonym TXPO:0004914 oboInOwl:hasExactSynonym
122 WARN duplicate_exact_synonym TXPO:0004394 oboInOwl:hasExactSynonym
123 WARN duplicate_exact_synonym TXPO:0004478 oboInOwl:hasExactSynonym
124 WARN duplicate_exact_synonym TXPO:0004953 oboInOwl:hasExactSynonym
125 WARN duplicate_exact_synonym TXPO:0005087 oboInOwl:hasExactSynonym
126 WARN duplicate_exact_synonym TXPO:0004950 oboInOwl:hasExactSynonym
127 WARN duplicate_exact_synonym TXPO:0005088 oboInOwl:hasExactSynonym
128 WARN duplicate_exact_synonym TXPO:0000967 oboInOwl:hasExactSynonym
129 WARN duplicate_exact_synonym TXPO:0003875 oboInOwl:hasExactSynonym
130 WARN duplicate_exact_synonym TXPO:0000791 oboInOwl:hasExactSynonym
131 WARN duplicate_exact_synonym TXPO:0002167 oboInOwl:hasExactSynonym
132 WARN duplicate_exact_synonym TXPO:0004778 oboInOwl:hasExactSynonym
133 WARN duplicate_exact_synonym TXPO:0004780 oboInOwl:hasExactSynonym
134 WARN duplicate_exact_synonym TXPO:0005129 oboInOwl:hasExactSynonym
135 WARN duplicate_exact_synonym TXPO:0000986 oboInOwl:hasExactSynonym
136 WARN duplicate_exact_synonym TXPO:0001072 oboInOwl:hasExactSynonym
137 WARN duplicate_exact_synonym TXPO:0001073 oboInOwl:hasExactSynonym
138 WARN duplicate_exact_synonym TXPO:0001076 oboInOwl:hasExactSynonym
139 WARN duplicate_exact_synonym TXPO:0000935 oboInOwl:hasExactSynonym
140 WARN duplicate_exact_synonym TXPO:0002309 oboInOwl:hasExactSynonym
141 WARN duplicate_exact_synonym TXPO:0004699 oboInOwl:hasExactSynonym
142 WARN duplicate_exact_synonym TXPO:0004701 oboInOwl:hasExactSynonym
143 WARN duplicate_exact_synonym TXPO:0002643 oboInOwl:hasExactSynonym
144 WARN duplicate_exact_synonym TXPO:0003266 oboInOwl:hasExactSynonym
145 WARN duplicate_exact_synonym TXPO:0004110 oboInOwl:hasExactSynonym
146 WARN duplicate_exact_synonym TXPO:0004111 oboInOwl:hasExactSynonym
147 WARN duplicate_exact_synonym TXPO:0001032 oboInOwl:hasExactSynonym
148 WARN duplicate_exact_synonym TXPO:0003263 oboInOwl:hasExactSynonym
149 WARN duplicate_label_synonym TXPO:0000158 oboInOwl:hasExactSynonym nuclear receptor activation
150 WARN duplicate_label_synonym TXPO:0001589 oboInOwl:hasExactSynonym nuclear receptor inactivation
151 WARN duplicate_label_synonym TXPO:0002501 oboInOwl:hasExactSynonym Peroxisome Proliferator-Activated Receptor Alpha [lipidosis]
152 WARN duplicate_label_synonym TXPO:0003178 oboInOwl:hasExactSynonym ROS accumulation [Glutathione depletion]
153 WARN duplicate_label_synonym TXPO:0003669 oboInOwl:hasExactSynonym small GTPase
154 WARN duplicate_label_synonym TXPO:0004446 oboInOwl:hasExactSynonym CAR activation
155 WARN duplicate_label_synonym TXPO:0004563 oboInOwl:hasExactSynonym GPCR
156 WARN equivalent_class_axiom_no_genus TXPO:0000369 RO:0002212 BFO:0000015
157 WARN equivalent_class_axiom_no_genus TXPO:0001223 RO:0002213 BFO:0000015
158 WARN invalid_xref TXPO:0000018 oboInOwl:hasDbXref IMR:0000328 (obsolete)
159 WARN invalid_xref TXPO:0000055 oboInOwl:hasDbXref R-HSA-381026
160 WARN invalid_xref TXPO:0000060 oboInOwl:hasDbXref Open TG-GatesID:FI-L0830
161 WARN invalid_xref TXPO:0000122 oboInOwl:hasDbXref Open TG-Gates compound_id=00030
162 WARN invalid_xref TXPO:0000138 oboInOwl:hasDbXref A size change process in which the size is increasing.
163 WARN invalid_xref TXPO:0000145 oboInOwl:hasDbXref FBRL: A Function and Behavior Representation Language. Sasajima, M., Kitamura, Y., Ikeda, M. & Mizoguchi, R., In Proc. of IJCAI-95 (pp. 1830-1836), 1995
164 WARN invalid_xref TXPO:0000173 oboInOwl:hasDbXref Reactome: R-HSA-211945
165 WARN invalid_xref TXPO:0000186 oboInOwl:hasDbXref IMR:0000196 (obsolete)
166 WARN invalid_xref TXPO:0000186 oboInOwl:hasDbXref related cell structure GO:0015630
167 WARN invalid_xref TXPO:0000225 oboInOwl:hasDbXref Cell damage (also known as cell injury) is a variety or changes of stress that a cell suffers due to external as well internal environmental changes. Among other causes, this can be due to physical, chemical, infectious, biological, nutritional or immunological factors. Cell damage can be reversible or irreversible. Depending on the extent of injury, the cellular response may be adaptive and where possible, homeostasis is restored. Cell death occurs when the severity of the injury exceeds the cell’s ability to repair itself. Cell death is relative to both the length of exposure to a harmful stimulus and the severity of the damage caused. Cell death may occur by necrosis or apoptosis.
168 WARN invalid_xref TXPO:0000330 oboInOwl:hasDbXref IMR:0000369 (obsolete)
169 WARN invalid_xref TXPO:0000376 oboInOwl:hasDbXref cell survival [ER stress]
170 WARN invalid_xref TXPO:0000494 oboInOwl:hasDbXref PMID: 9061852
171 WARN invalid_xref TXPO:0000599 oboInOwl:hasDbXref MeSH: C000607812
172 WARN invalid_xref TXPO:0000622 oboInOwl:hasDbXref IMR:0000006 (obsolete)
173 WARN invalid_xref TXPO:0000624 oboInOwl:hasDbXref IMR:0000002 (obsolete)
174 WARN invalid_xref TXPO:0000633 oboInOwl:hasDbXref Rubin Pathology
175 WARN invalid_xref TXPO:0000666 oboInOwl:hasDbXref NCBI-Mouse-GeneID: 230163
176 WARN invalid_xref TXPO:0000666 oboInOwl:hasDbXref NCBI-Rat-GeneID: 24190
177 WARN invalid_xref TXPO:0000698 oboInOwl:hasDbXref R-HSA-380994
178 WARN invalid_xref TXPO:0000790 oboInOwl:hasDbXref Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells. 2-(2-chlorophenyl)ethylbiguanide (2-Cl-Phen) down-regulated expression of several ER stress-related genes, with the exception of GADD153. The expression levels of ATF6α, GRP78, MANF, and CRELD2 mRNA were almost completely decreased by 2-Cl-Phen.
179 WARN invalid_xref TXPO:0000800 oboInOwl:hasDbXref R-HSA-1791066.1
180 WARN invalid_xref TXPO:0000834 oboInOwl:hasDbXref fatty acid
181 WARN invalid_xref TXPO:0000844 oboInOwl:hasDbXref Reactome: R-HSA-844456.2
182 WARN invalid_xref TXPO:0000885 oboInOwl:hasDbXref IMR:0000653 (obsolete)
183 WARN invalid_xref TXPO:0001007 oboInOwl:hasDbXref OMIM: 600811
184 WARN invalid_xref TXPO:0001020 oboInOwl:hasDbXref OMIM: 611583
185 WARN invalid_xref TXPO:0001047 oboInOwl:hasDbXref The birth rate of Elovl6 knockout mice was lower, and the surviving mice were smaller in size and had reduced body weight. Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. Secondary regulation of PPARa activity could be a part of SREBP-1c/Elovl6 regulation of lipogenesis.
186 WARN invalid_xref TXPO:0001057 oboInOwl:hasDbXref ACOT3 is involved in the transport of DCAdicarboxylic acids into the peroxisomes by hydrolysis of long-medium chain fatty acyl-CoA esters to FFA, which can be further transported out of peroxisomes to mitochondria for beta-oxidation or excreted in the urinPMID:23359794 At the gene level, this was reflected by the up-regulation of cytochrome P450 (Cyp) 4a10, Cyp4a14, Cyp4a31 and Acyl-CoA thioesterase 3 (Acot3). Two relevant regulators, cytochrome P450 oxidoreductase (Por, rate limiting for cytochrome P450s) and the transcription factor constitutive androstane receptor (Car; official symbol Nr1i3) were also up-regulated in the quercetin-fed mice.
187 WARN invalid_xref TXPO:0001094 oboInOwl:hasDbXref EC 1.1.1.1
188 WARN invalid_xref TXPO:0001159 oboInOwl:hasDbXref Orthologs of the human CYP2B6 genes can be found in other species including rats, mice, and dogs, which are termed Cyp2b1, Cyp2b10, and CYP2B11, respectively
189 WARN invalid_xref TXPO:0001187 oboInOwl:hasDbXref chronic ethanol-induced activation of KCs is attributed to gut-sourced LPS, which is a major component of outer membrane of Gram-negative bacteria and passes through the intestinal epithelial barrier. Chronic ethanol exposure can increase translocation of LPS from gut to liver by enhancing the intestinal permeability and altering the gut microflora.
190 WARN invalid_xref TXPO:0001252 oboInOwl:hasDbXref The birth rate of Elovl6 knockout mice was lower, and the surviving mice were smaller in size and had reduced body weight. Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. Secondary regulation of PPARa activity could be a part of SREBP-1c/Elovl6 regulation of lipogenesis.
191 WARN invalid_xref TXPO:0001277 oboInOwl:hasDbXref
192 WARN invalid_xref TXPO:0001395 oboInOwl:hasDbXref ASAH1 is an estrogen-dependent member of the sphingolipid metabolism, which might provide further prognostic information in ER-positive breast cancers.
193 WARN invalid_xref TXPO:0001441 oboInOwl:hasDbXref wikipedia: Deletion_(genetics)
194 WARN invalid_xref TXPO:0001744 oboInOwl:hasDbXref Reactome: R-HSA-844456.2
195 WARN invalid_xref TXPO:0001766 oboInOwl:hasDbXref hypofunction of glucuronic acid conjugation
196 WARN invalid_xref TXPO:0001785 oboInOwl:hasDbXref EC 3.1.4.12
197 WARN invalid_xref TXPO:0001797 oboInOwl:hasDbXref G6PC [Ground glass appearance]
198 WARN invalid_xref TXPO:0001798 oboInOwl:hasDbXref The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
199 WARN invalid_xref TXPO:0001830 oboInOwl:hasDbXref decreasing protein production