Level Rule Name Subject Property Value WARN duplicate_scoped_synonym CL:4023016 oboInOwl:hasBroadSynonym VIP neuron WARN duplicate_scoped_synonym CL:4023016 oboInOwl:hasRelatedSynonym VIP neuron WARN missing_definition CL:0000028 IAO:0000115 WARN missing_definition CL:0000069 IAO:0000115 WARN missing_definition CL:0000072 IAO:0000115 WARN missing_definition CL:0000095 IAO:0000115 WARN missing_definition CL:0000109 IAO:0000115 WARN missing_definition CL:0000117 IAO:0000115 WARN missing_definition CL:0000123 IAO:0000115 WARN missing_definition CL:0000130 IAO:0000115 WARN missing_definition CL:0000143 IAO:0000115 WARN missing_definition CL:0000146 IAO:0000115 WARN missing_definition CL:0000149 IAO:0000115 WARN missing_definition CL:0000159 IAO:0000115 WARN missing_definition CL:0000204 IAO:0000115 WARN missing_definition CL:0000208 IAO:0000115 WARN missing_definition CL:0000237 IAO:0000115 WARN missing_definition CL:0000238 IAO:0000115 WARN missing_definition CL:0000246 IAO:0000115 WARN missing_definition CL:0000249 IAO:0000115 WARN missing_definition CL:0000251 IAO:0000115 WARN missing_definition CL:0000253 IAO:0000115 WARN missing_definition CL:0000256 IAO:0000115 WARN missing_definition CL:0000306 IAO:0000115 WARN missing_definition CL:0000308 IAO:0000115 WARN missing_definition CL:0000309 IAO:0000115 WARN missing_definition CL:0000310 IAO:0000115 WARN missing_definition CL:0000311 IAO:0000115 WARN missing_definition CL:0000314 IAO:0000115 WARN missing_definition CL:0000323 IAO:0000115 WARN missing_definition CL:0000324 IAO:0000115 WARN missing_definition CL:0000326 IAO:0000115 WARN missing_definition CL:0000327 IAO:0000115 WARN missing_definition CL:0000334 IAO:0000115 WARN missing_definition CL:0000341 IAO:0000115 WARN missing_definition CL:0000354 IAO:0000115 WARN missing_definition CL:0000356 IAO:0000115 WARN missing_definition CL:0000357 IAO:0000115 WARN missing_definition CL:0000367 IAO:0000115 WARN missing_definition CL:0000376 IAO:0000115 WARN missing_definition CL:0000377 IAO:0000115 WARN missing_definition CL:0000378 IAO:0000115 WARN missing_definition CL:0000379 IAO:0000115 WARN missing_definition CL:0000383 IAO:0000115 WARN missing_definition CL:0000384 IAO:0000115 WARN missing_definition CL:0000389 IAO:0000115 WARN missing_definition CL:0000390 IAO:0000115 WARN missing_definition CL:0000406 IAO:0000115 WARN missing_definition CL:0000410 IAO:0000115 WARN missing_definition CL:0000416 IAO:0000115 WARN missing_definition CL:0000417 IAO:0000115 WARN missing_definition CL:0000423 IAO:0000115 WARN missing_definition CL:0000428 IAO:0000115 WARN missing_definition CL:0000435 IAO:0000115 WARN missing_definition CL:0000436 IAO:0000115 WARN missing_definition CL:0000445 IAO:0000115 WARN missing_definition CL:0000447 IAO:0000115 WARN missing_definition CL:0000457 IAO:0000115 WARN missing_definition CL:0000470 IAO:0000115 WARN missing_definition CL:0000489 IAO:0000115 WARN missing_definition CL:0000490 IAO:0000115 WARN missing_definition CL:0000520 IAO:0000115 WARN missing_definition CL:0000529 IAO:0000115 WARN missing_definition CL:0000544 IAO:0000115 WARN missing_definition CL:0000551 IAO:0000115 WARN missing_definition CL:0000567 IAO:0000115 WARN missing_definition CL:0000618 IAO:0000115 WARN missing_definition CL:0000619 IAO:0000115 WARN missing_definition CL:0000661 IAO:0000115 WARN missing_definition CL:0000662 IAO:0000115 WARN missing_definition CL:0000676 IAO:0000115 WARN missing_definition CL:0000684 IAO:0000115 WARN missing_definition CL:0000687 IAO:0000115 WARN missing_definition CL:0000690 IAO:0000115 WARN missing_definition CL:0000694 IAO:0000115 WARN missing_definition CL:0000697 IAO:0000115 WARN missing_definition CL:0000702 IAO:0000115 WARN missing_definition CL:0000705 IAO:0000115 WARN missing_definition CL:0000707 IAO:0000115 WARN missing_definition CL:0000709 IAO:0000115 WARN missing_definition CL:0000713 IAO:0000115 WARN missing_definition CL:0000719 IAO:0000115 WARN missing_definition CL:0000720 IAO:0000115 WARN missing_definition CL:0000721 IAO:0000115 WARN missing_definition CL:0000722 IAO:0000115 WARN missing_definition CL:0000732 IAO:0000115 WARN missing_definition CL:0000995 IAO:0000115 WARN missing_definition CL:0001012 IAO:0000115 WARN missing_definition CL:0001019 IAO:0000115 WARN missing_definition CL:0001030 IAO:0000115 WARN missing_definition CL:0001658 IAO:0000115 WARN missing_definition CL:0007019 IAO:0000115 WARN missing_definition CL:0010013 IAO:0000115 WARN missing_definition CL:0010014 IAO:0000115 WARN missing_definition CL:1000082 IAO:0000115 WARN missing_definition CL:1000083 IAO:0000115 WARN missing_definition CL:1000085 IAO:0000115 WARN missing_definition CL:1000691 IAO:0000115 WARN missing_definition CL:1000695 IAO:0000115 WARN missing_definition CL:1000696 IAO:0000115 WARN missing_definition CL:1000697 IAO:0000115 WARN missing_definition CL:1001064 IAO:0000115 WARN missing_definition CL:1001066 IAO:0000115 WARN missing_definition CL:1001068 IAO:0000115 WARN missing_definition CL:4023032 IAO:0000115 WARN missing_definition CL:4030044 IAO:0000115 WARN missing_definition CL:4030045 IAO:0000115 WARN missing_definition CL:4030046 IAO:0000115 WARN missing_subset_declaration obo:cl#cellxgene_subset rdfs:subPropertyOf INFO lowercase_definition CL:0011111 IAO:0000115 a specialized neuroendocrine cell that synthesizes and secretes GnRH decapeptide, a key regulator of reproductive function. It originates from the olfactory placode during embryonic development and migrates into the forebrain where it localises predominantly in the hypothalamus and in humans, in extrahypothalamic regions like the basal ganglia (Skrapits et al., 2021). This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation. It expresses receptor subunits required for AMPA, NMDA, and kainate receptor signaling and may use glutamate as a neurotransmitter in recurrent collateral innervation. INFO lowercase_definition CL:4023080 IAO:0000115 a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has stellate pyramidal morphology. INFO lowercase_definition CL:4023081 IAO:0000115 a L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex that has inverted pyramidal morphology. INFO lowercase_definition CL:4023127 IAO:0000115 a KNDy neuron that is located in the arcuate nucleus of the hypothalamus. INFO lowercase_definition CL:4023128 IAO:0000115 a KNDy neuron that is located in the rostral periventricular region of the third ventricle. INFO lowercase_definition CL:4052051 IAO:0000115 ​​A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018). It expresses the uterine resident marker CD49a and is distinguished from uNK2 and uNK3 by CD39 expression and the absence of CD103 (Whettlock et al., 2022) and CD160 (Marečková et al., 2024). It also expresses higher levels of killer-cell immunoglobulin-like receptors (KIRs) and leukocyte immunoglobulin-like receptor B1 (LILRB1), which facilitate interaction with human leukocyte antigens (HLAs) on extravillous trophoblast cells, promoting immune tolerance and implantation. Enriched in the endometrium post-ovulation (Marečková et al., 2024) and prominent in early pregnancy (Whettlock et al., 2022), uNK1 regulates trophoblast invasion and spiral artery remodeling (Zhang & Wei, 2021).